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The Pituitary, Fifth Edition, continues the tradition of a cogent blend of basic science and clinical medicine which was the successful hallmark of prior editions. The comprehensive text written by expert pituitary scholars are devoted to the pathogenesis, diagnosis, and treatment of pituitary disorders. The new fifth edition has been extensively revised to reflect the most recent data on new research advances in tumorigenesis and new therapeutic approaches for pituitary tumors, particularly in acromegaly and Cushing disease. Notably, new chapters devoted to the Pituitary-Immune Interface and Pituitary Radiotherapy have been included, and a chapter on Aggressive Pituitary Adenomas have been developed to align with the WHO Classification of Pituitary Tumors. Furthermore, new authors have been invited, ensuring a fresh perspective on critical issues in the field.This extensive bo dy of knowledge is useful for students, trainees, physicians, and scientists who need to understand critical pituitary functions and how to care for patients with pituitary disorders. Provides a detailed description of the wide spectrum of clinical disorders emanating from dysfunction of the “master gland and the fundamental science underlying pituitary dysfunction Brings together pituitary experts from all areas of research and practice who take readers all the way from bench research, to genomic and proteomic analysis, clinical analysis, and new therapeutic approaches to pituitary disorders Describes the mechanisms for disease pathogenesis, including both subcellular and extrinsic mechanisms subserving normal and disordered pituitary hormone secretion and action Saves researchers and clinicians time in quickly accessing the very latest details on a broad range of issues related to normal and diseased pituitary function