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This volume provides a comprehensive and clear outline of microRNA pathophysiology, with the most updated notions and recently discovered pathways in several processes, including aging, diabetes, cardiovascular disease, hematopoiesis, and mitochondrial fitness. It covers up-to-date basic concepts on these tiny molecules, discussed by leading scientists in the field, worldwide renowned, working in prestigious universities. The present book represents the first volume - focused on molecular and cellular biology and basic science-of a trilogy exploring the functional roles of microRNAs from biology to the clinical scenario. The second volume addresses cancer and the third one provides an overview of the clinical importance of microRNAs. The book includes numerous color photographs, schemes, diagrams of molecular pathways, and tables that support and complement the text.§In summary, the book provides a current, state-of-the-art overview of the literature of this expanding and fascinating field. The three volumes will be of value to medical students, physicians, and researchers, as a complete and unique guide in the exploration of microRNA from biology to clinical practice.§