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In this first volume of his history of epidemics in Britain, controversial physician Charles Creighton begins his examination of diseases in Britain from the first British epidemic in 664 AD to the end of the Great Plague in 1666. The work is broken down by time period and disease, ranging from Bede's record of the plague of 664–684 to 'the French pox', as well as outbreaks during sea voyages and in the early colonies. This work will be of value to medical historians and those with an interest in epidemiology.