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Heteroaromatic Lipoxin A4 Analogues

Jezik EngleskiEngleski
Knjiga Tvrdi uvez
Knjiga Heteroaromatic Lipoxin A4 Analogues Colm Duffy
Libristo kod: 01659048
Nakladnici Springer-Verlag Berlin and Heidelberg GmbH & Co. KG, prosinac 2011
In this thesis Colm Duffy reviews the chemistry and biology of stable lipoxin analogues. Colm has pr... Cijeli opis
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In this thesis Colm Duffy reviews the chemistry and biology of stable lipoxin analogues. Colm has prepared for the first time ever a pyridine-containing LXA4 analogue in enantiomerically pure form. Biological evaluation determined that both epimers at the benzylic position suppress key cytokines known to be involved in inflammatory disease, with the (R)-epimer proving most efficacious. Moreover the author developed an excellent route to a related thiophene-containing analogue that also showed interesting biological activity. Both routes have inspired further work in the synthesis of further heteroaromatic analogues for biological evaluation.

Informacije o knjizi

Puni naziv Heteroaromatic Lipoxin A4 Analogues
Autor Colm Duffy
Jezik Engleski
Uvez Knjiga - Tvrdi uvez
Datum izdanja 2011
Broj stranica 130
EAN 9783642246319
ISBN 3642246311
Libristo kod 01659048
Nakladnici Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Težina 401
Dimenzije 155 x 235 x 13

Kategorija

Mathematics & Science > Chemistry > Physical chemistry > Catalysis
Mathematics & Science > Biology, life sciences > Biochemistry
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