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This status report features the most recent developments in the field, spanning a wide range of topical areas in the computer simulation of condensed matter/materials physics. Both established and new topics are included, ranging from the statistical mechanics of classical magnetic spin models to electronic structure calculations, quantum simulations, and simulations of soft condensed matter.This volume represents a "status report" emanating from presentations made during the 19th Annual Workshop on Computer Simulations Studies in Condensed Matter Physics at the Center for Simulational Physics at the University of Georgia in February, 2006. It provides a broad overview of the most recent advances in the field, spanning the range from equilibrium and non-equilibrium behavior in statistical physics to biological and soft condensed matter systems. Results on nanomagents and materials are included as are several descriptions of advances in methodology.