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This volume critically reviews the state of the art in C-H activation chemistry. In particular, methods are examined by which a wide variety of bonds to carbon (i.e., C-C, C-Hal, C-N, C-O, and C-B bonds) may be formed, with specific focus upon the nature of the substrate, the transition-metal catalyst, and the reagent used.§§"Science of Synthesis: Catalytic Transformations via C-H Activation" serves as a basis for the practical application of the techniques discussed, and lays the foundation for future research. In the tradition of Science of Synthesis, the reference work presents the state of the art by experts in the field and includes typical or general experimental procedures for the best methods.