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Bioprocess Engineering Principles, Third Edition provides a solid introduction to bioprocess engineering for students with a limited engineering background. It explains process analysis from an engineering perspective, using worked examples and problems that relate to biological systems. Application of engineering concepts is illustrated in areas of modern biotechnology, such as recombinant protein production, bioremediation, biofuels, drug development, and tissue engineering, as well as microbial fermentation. With new and expanded material, Doran remains the book of choice for students seeking to move into bioprocess engineering More than 350 problems in the book now demonstrate how the fundamental principles are applied in areas such as biofuels, bioplastics, bioremediation, tissue engineering, site-directed mutagenesis, recombinant protein production, and drug development, as well as for traditional microbial fermentation Provides in-depth treatment of fluid flow, turbulence, mixing, and impeller design, reflecting recent advances in our understanding of mixing processes and their importance in determining the performance of cell cultures Focuses on underlying scientific and engineering principles rather than on specific biotechnology applications, providing a sound basis for teaching bioprocess engineering Topics such as fluid flow and mixing, heat and mass transfer, reaction engineering, and downstream processing are presented in detail as they apply to bioprocessing Includes new or expanded coverage of such topics as enzyme kinetics, downstream processing, disposable reactors, genetic engineering, and the technology of fermentation